![]() However, unlike the latter two drugs, orforglipron is administered as a once-a-day pill rather than an injection, which should make it much more attractive to users. ![]() Lilly's experimental drug orforglipron comes from the blockbuster class of diabetes/ weight-loss meds called glucagon-like peptide-1 agonists (GLP-1 agonists) that include Ozempic and Wegovy. ![]() In that trial, the drug helped people with type 2 diabetes shed excess weight. Published simultaneously in The Lancet and the New England Journal of Medicine, trials of two diabetes drugs from Eli Lilly-Mounjaro, an injected drug which is already available to patients, and orforglipron, still in clinical trials-each showed effectiveness in helping users drop pounds.Īlso presented at the meeting and published in The Lancet, Novo Nordisk released the results of a trial of its new investigational drug, dubbed CagriSema, which contains semaglutide (Ozempic) plus a newer medication, cagrilintide. ![]() Other pharmaceutical giants took notice, and over the past weekend the results of multiple clinical trials from would-be competitors were unveiled at this year's annual meeting of the American Diabetes Association (ADA).
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